Open Year Round, 11am-1am, 7 Days. Serving Lunch and Dinner. Located "West of the Rotary" on Route 132 (950 Iyanough Road) in the Hyannis shopping district across from the Cape Cod Mall. Sam Diego's offers bountiful plates of Mexican & Southwestern cuisine, award-winning ribs, salads, sandwiches, burgers and a special children's menu. Seasonal patio dining. 2 bars. Eclectic Southwestern atmosphere.